Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
dacB nonessential low molecular mass PBP4	T428P	-	inactivation, D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB	Pseudomonas aeruginosa	ceftazidimecephalosporins	Reference Gene CatalogReslit	Confirmed
dacB nonessential low molecular mass PBP4	T79P	-	inactivation	Pseudomonas aeruginosa	ceftazidimecefepimepiperacillin+1 more	Reslit	Candidate
dacB nonessential low molecular mass PBP4	W273X	-	inactivation	Pseudomonas aeruginosa	ceftazidimecefepimepiperacillin+1 more	Reslit	Candidate
dacB penicillin-binding protein PBP4	W388L	-	-	Pseudomonas aeruginosa	ceftazidime avibactam	Reslit	Candidate
dacB	W459*	-	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB	Pseudomonas aeruginosa	cephalosporins	Reference Gene Catalog	Established
dacB	W92R	-	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB	Pseudomonas aeruginosa	cephalosporins	Reference Gene Catalog	Established
dacS two-component system histidine kinase	E238D	-	two-component sensor histidine kinase DacS	Clostridioides difficile	vancomycin	Reference Gene CatalogReslit	Confirmed
dacS two-component system histidine kinase	L183P	-	-	Clostridioides difficile	vancomycin	Reslit	Candidate
dacS two-component system histidine kinase	V183A	-	two-component sensor histidine kinase DacS	Clostridioides difficile	vancomycin	Reference Gene CatalogReslit	Confirmed
dacS two-component system histidine kinase	V238M	-	-	Clostridioides difficile	vancomycin	Reslit	Candidate