Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
ddn F420-dependent mycobacterial nitroreductase | T79R | - | - | Mycobacterium avium | delamanid | Reslit | Candidate |
ddn deazaflavin-dependent nitroreductase | V148I | - | - | Mycobacterium smegmatis | pa 824 | Reslit | Candidate |
ddn deazaflavin-dependent nitroreductase | V75L | - | - | Mycobacterium smegmatis | pa 824 | Reslit | Candidate |
| W139* | - | nonsense mutation | Mycobacterium tuberculosis | multiple antibiotics | Card Database | Established | |
ddn deazaflavin-dependent nitroreductase | W20* | - | nonsense mutation | Mycobacterium tuberculosis | delamanidpretomanidmultiple antibiotics | Card DatabaseReslit | Confirmed |
ddn nitroimidazole reductase | W88* | loss-of-function, nonsense mutation | Mycobacterium tuberculosis | delamanidpretomanidmultiple antibiotics | Card DatabaseReslit | Confirmed | |
ddn deazaflavin-dependent nitroreductase | W88R | - | - | - | pretomanid | Reslit | Candidate |
ddn deazaflavin-dependent nitroreductase | Y133C | - | - | - | pretomanid | Reslit | Candidate |
ddn deazaflavin-dependent nitroreductase | Y133F | - | - | Mycobacterium smegmatis | pa 824 | Reslit | Candidate |
ddn deazaflavin-dependent nitroreductase | Y65L | - | - | Mycobacterium smegmatis | pa 824 | Reslit | Candidate |
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