Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
ddn F420-dependent mycobacterial nitroreductase | Y89S | - | - | Mycobacterium tuberculosis | delamanid | Reslit | Candidate |
deoD2 purine nucleoside phosphorylase | G278* | - | - | Staphylococcus aureus | oxacillin | Reslit | Candidate |
dfrA dihydrofolate reductase | - | - | Mycobacterium tuberculosis | para aminosalicylic acid | Reslit | Candidate | |
dfrA dihydrofolate reductase | - | - | Mycobacterium tuberculosis | pas | Reslit | Candidate | |
dfrA dihydrofolate reductase | F98I | - | - | Staphylococcus aureus | trimethoprim | Reslit | Candidate |
dfrA dihydrofolate reductase | F98Y | - | - | Staphylococcus aureus | trimethoprim | Reslit | Candidate |
dfrA trimethoprim target | F99Y | - | - | Staphylococcus aureus | trimethoprim | Reslit | Candidate |
dfrA1 dihydrofolate reductase | D27E | - | increased ligand dissociation rates while maintaining the enzyme’s ability to turnover substrate | Escherichia coli, Salmonella enterica | trimethoprim | Reslit | Candidate |
dfrA5 dihydrofolate reductase | D27E | - | - | - | trimethoprim | Reslit | Candidate |
dfrA5 dihydrofolate reductase | L28Q | - | - | - | trimethoprim | Reslit | Candidate |
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