Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA DNA gyrase subunit A	E85A	-	-	Streptococcus pneumoniae, Streptococcus agalactiae	moxifloxacinlevofloxacingemifloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	E85G	-	-	Acinetobacter baumannii, Streptococcus pneumoniae	fluoroquinolonesciprofloxacinnalidixic acid	Reslit	Supported
gyrA DNA gyrase subunit A	E85K	G253A G254A GAG->AAA G255A	mutation in DNA gyrase subunit A	Streptococcus pneumoniae, Streptococcus agalactiae, Streptococcus pyogenes, Streptococcus suis	levofloxacinfluoroquinolonesmoxifloxacin+5 more	Reslit	Supported
gyrA DNA gyrase subunit A	E85V	-	-	Acinetobacter baumannii	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	E86K	-	-	Staphylococcus aureus	ciprofloxacinlevofloxacinmoxifloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	E871K	-	-	Staphylococcus pseudintermedius	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	E87G	-	Target modification, DNA gyrase subunit A GyrA	Mycoplasma gallisepticum, Enterococcus faecalis, Enterococcus faecium	danofloxacinenrofloxacinofloxacin+6 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	E87K	GAG -> AAA GAG->AAA	Target modification, DNA gyrase subunit A GyrA	Streptococcus pneumoniae, Enterococcus faecalis, Enterococcus faecium	ciprofloxacinfluoroquinolonesgrepafloxacin+5 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA	E87L	-	Target modification, DNA gyrase subunit A GyrA	Enterococcus faecalis, Enterococcus faecium	nalidixic acidciprofloxacinquinolones	Reference Gene CatalogResFinder Database	Confirmed
gyrA DNA gyrase subunit A	E87Q	-	-	Acinetobacter baumannii	fluoroquinolones	Reslit	Candidate