Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	E87Y	-	DNA gyrase subunit A GyrA	Enterococcus faecalis	quinolones	Reference Gene Catalog	Established
gyrA DNA gyrase subunit A	E88A	-	single resistance variant, DNA gyrase subunit A GyrA	Staphylococcus coagulans, Staphylococcus aureus	ciprofloxacinenrofloxacinfluoroquinolones+1 more	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrA DNA gyrase A subunit	E88G	-	Target modification, DNA gyrase subunit A GyrA	Staphylococcus pseudintermedius, Staphylococcus coagulans, Enterococcus faecalis, Staphylococcus aureus	enrofloxacinciprofloxacinfluoroquinolones+1 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	E88K	-	Target modification, single resistance variant, DNA gyrase subunit A GyrA	Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pneumoniae, Staphylococcus pseudintermedius	ciprofloxacinmoxifloxacinfluoroquinolones+4 more	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA	E88L	-	Target modification, DNA gyrase subunit A GyrA	Staphylococcus aureus	ciprofloxacinquinolones	Reference Gene CatalogResFinder Database	Confirmed
gyrA	E88R	-	DNA gyrase subunit A GyrA	Staphylococcus aureus	quinolones	Reference Gene Catalog	Established
gyrA DNA gyrase subunit A	E88V	-	-	Staphylococcus aureus	ciprofloxacinlevofloxacinmoxifloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	E90V	-	-	-	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	E92K	-	alterations in topoisomerase IV	Salmonella enterica	ciprofloxacinnalidixic acid	Reslit	Candidate
gyrA DNA gyrase subunit A	E94K	G280A	-	-	fluoroquinolones	Reslit	Supported