Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA DNA gyrase subunit A	S79Y	-	-	-	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase A	S80F	TCT -> TTC	-	Staphylococcus epidermidis, Staphylococcus coagulans, S. epidermidis	ciprofloxacinofloxacingatifloxacin+3 more	Reslit	Supported
gyrA DNA gyrase subunit A	S80I	TCA->ATA	confers resistance to fluoroquinolones, harbored mutations gyrA (S83F), gyrA (D87Y), and parC (S80I) associated with resistance to quinolones	Escherichia coli, Salmonella enterica	enrofloxacinfluoroquinolonesciprofloxacin+3 more	Reslit	Supported
gyrA DNA gyrase subunit A	S80L	-	-	Staphylococcus aureus	moxifloxacinciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	S80R	-	-	Salmonella enterica, Escherichia coli	ciprofloxacinfluoroquinolones	Reslit	Candidate
gyrA DNA gyrase A	S80Y	-	-	Staphylococcus epidermidis	ciprofloxacinofloxacingatifloxacin+2 more	Reslit	Candidate
gyrA DNA gyrase subunit A	S81A	-	-	Streptococcus pneumoniae	moxifloxacinlevofloxacingemifloxacin+1 more	Reslit	Candidate
gyrA DNA gyrase subunit A	S81F	AGT -> TTC AGT->TTT GCA->TTA C244T G242T T243C	confers resistance, resistance	Streptococcus pneumoniae, Staphylococcus aureus, Streptococcus dysgalactiae, Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus suis	clinafloxacinciprofloxacintrovafloxacin+10 more	Reslit	Supported
gyrA DNA gyrase subunit	S81I	-	-	Streptococcus pneumoniae	ciprofloxacinlevofloxacinmoxifloxacin+4 more	Reslit	Candidate
gyrA DNA gyrase subunit A	S81L	TCC->CTC TCA->CTA	lower the affinity for quinolone, resistance, mutations in gyrA and parC genes, confers high-level resistance to fluoroquinolones, single resistance variant, DNA gyrase subunit A GyrA	Streptococcus pneumoniae, Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa, Streptococcus agalactiae, Streptococcus pyogenes, Streptococcus oralis, Streptococcus mitis, Neisseria gonorrhoeae, A. baumannii, Acinetobacter pittii, Acinetobacter nosocomialis, Non-baumannii Acinetobacter	clinafloxacinciprofloxacintrovafloxacin+5 more	Card DatabaseReference Gene CatalogReslit	Confirmed