Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	S85A	-	DNA gyrase subunit A GyrA	Staphylococcus pseudintermedius	quinolones	Reference Gene Catalog	Established
gyrA DNA gyrase subunit A	S85F	-	-	Vibrio cholerae, Escherichia coli	ciprofloxacinnalidixic acid	Reslit	Candidate
gyrA DNA gyrase subunit A	S85L	-	reduced susceptibility to fluoroquinolones	Bacillus anthracis, E. coli	ciprofloxacinmoxifloxacinfluoroquinolones	Reslit	Supported
gyrA DNA gyrase subunit A	S85P	-	Target modification, single resistance variant, DNA gyrase subunit A GyrA	Staphylococcus aureus	ciprofloxacinlevofloxacinfluoroquinolones+2 more	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	S864P	-	-	Salmonella enterica	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	S86L	C257T	-	Campylobacter jejuni, Campylobacter coli, Campylobacter spp.	quinolonesciprofloxacinnalidixic acid+1 more	Reslit	Supported
gyrA DNA gyrase subunit A	S87A	AGC->GCC	-	Corynebacterium provencense	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	S87F	-	confers resistance	Corynebacterium striatum, Staphylococcus aureus, Campylobacter jejuni, Corynebacterium spp., Salmonella enterica	ciprofloxacinlevofloxacinfluoroquinolones+1 more	Reslit	Supported
gyrA DNA gyrase subunit A	S87G	-	-	Escherichia coli	ciprofloxacinnorfloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	S87I	-	-	Corynebacterium amycolatum, Corynebacterium spp., Corynebacterium jeikeium, Corynebacterium urealyticum	ciprofloxacinfluoroquinoloneslevofloxacin+1 more	Reslit	Supported