Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
gyrB DNA gyrase subunit B | D427N | - | - | - | levofloxacinmoxifloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D429N | increased zoliflodacin MICs, increased MICs of zoliflodacin, single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Neisseria gonorrhoeae, Neisseria subflava | zoliflodacin | Card DatabaseReference Gene CatalogReslit | Confirmed | |
gyrB DNA gyrase B subunit | D429V | - | - | Neisseria gonorrhoeae | zoliflodacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D432N | - | - | - | ciprofloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D435E | - | - | Streptococcus pneumoniae | ciprofloxacinofloxacinlevofloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D435G | - | - | Streptococcus pneumoniae | levofloxacinsparfloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D435N | - | - | Helicobacter pylori | levofloxacin | Reslit | Candidate |
| D436N | - | DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Staphylococcus aureus | quinolones | Reference Gene Catalog | Established | |
gyrB DNA gyrase subunit B | D437E | - | - | Staphylococcus aureus | nemonoxacinmoxifloxacinlevofloxacin+1 more | Reslit | Candidate |
gyrB DNA gyrase subunit B | D443A | - | - | - | levofloxacinmoxifloxacin | Reslit | Candidate |
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