Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
gyrB DNA gyrase subunit B | D443N | - | - | - | levofloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D460G | - | - | fluoroquinolones | Reslit | Candidate | |
| D461A | - | - | Mycobacterium tuberculosis | fluoroquinolones | ResFinder Database | Established | |
gyrB DNA gyrase subunit B | D461H | - | single resistance variant | Mycobacterium tuberculosis | fluoroquinolonesofloxacinmoxifloxacin+2 more | Card DatabaseResFinder DatabaseReslit | Confirmed |
gyrB DNA gyrase subunit B | D461N | single resistance variant | Mycobacterium tuberculosis | fluoroquinolonesofloxacinmoxifloxacin+3 more | Card DatabaseResFinder DatabaseReslit | Confirmed | |
gyrB DNA gyrase B subunit | D464N | single resistance variant | Mycobacterium leprae | ofloxacinmoxifloxacinsitafloxacin+3 more | Card DatabaseReslit | Confirmed | |
gyrB DNA gyrase subunit B | D465N | - | Clostridioides difficile | levofloxacinciprofloxacinfluoroquinolones | Reslit | Candidate | |
| D465Y | - | single resistance variant | Clostridium ljungdahlii | fluoroquinolones | Card Database | Established | |
gyrB DNA gyrase subunit B | D468N | - | - | Clostridioides difficile | fluoroquinolones | Reslit | Candidate |
gyrB DNA gyrase subunit B | D472A | - | - | - | fluoroquinolonesofloxacinmoxifloxacin+2 more | Reslit | Candidate |
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