Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
gyrB fluoroquinolone resistance | D472G | - | - | Mycobacterium tuberculosis | ciprofloxacinfluoroquinoloneslevofloxacin+2 more | Reslit | Candidate |
gyrB DNA gyrase subunit B | D472H | - | - | Mycobacterium tuberculosis | fluoroquinolonesofloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D472N | - | - | Mycobacterium tuberculosis | ofloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D472V | - | - | Mycobacterium tuberculosis | ofloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | D473N | - | - | - | fluoroquinolones | Reslit | Candidate |
gyrB DNA gyrase subunit B | D481E | - | co-dependent single resistance variant | Helicobacter pylori | levofloxacinfluoroquinolones | Card DatabaseReslit | Confirmed |
gyrB DNA gyrase subunit B | D484K | - | co-dependent single resistance variant | Helicobacter pylori | fluoroquinolones | Card DatabaseReslit | Confirmed |
gyrB DNA gyrase subunit B | D487E | - | - | Francisella novicida | fluoroquinolones | Reslit | Candidate |
| D494A | - | - | Mycobacterium tuberculosis | fluoroquinolones | ResFinder Database | Established | |
gyrB DNA gyrase B | D494N | - | - | Staphylococcus aureus | ciprofloxacin | Reslit | Candidate |
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