Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
inhA enoyl-ACP reductase	I16T	-	reduce NADH affinity, single resistance variant	Mycobacterium tuberculosis	isoniazid	Card DatabaseResFinder DatabaseReslit	Confirmed
inhA enoyl-(acyl-carrier-protein) reductase	I194A	-	-	-	isoniazid	Reslit	Candidate
inhA Enoyl-(acyl-carrier-protein) reductase	I194T	ATT > ACC	single resistance variant	Mycobacterium tuberculosis	isoniazidethionamide	Card DatabaseResFinder DatabaseReslit	Confirmed
inhA	I21N	-	-	Mycobacterium tuberculosis	isoniazid	ResFinder Database	Established
inhA Enoyl-(acyl-carrier-protein) reductase	I21T	T62C	single resistance variant	Mycobacterium tuberculosis	isoniazidethionamide	Card DatabaseResFinder DatabaseReslit	Confirmed
inhA Enoyl-(acyl-carrier-protein) reductase	I21V	A61G A63T A63G	reduce NADH affinity, single resistance variant	Mycobacterium tuberculosis	isoniazidethionamide	Card DatabaseResFinder DatabaseReslit	Confirmed
inhA enoyl-(acyl-carrier-protein) reductase	I25T	T74C	-	Mycobacterium tuberculosis	isoniazid	Reslit	Candidate
inhA enoyl reductase	I47T	A141C	single resistance variant	Mycobacterium tuberculosis	isoniazid	Card DatabaseResFinder DatabaseReslit	Confirmed
inhA Enoyl-(acyl-carrier-protein) reductase	I95P	-	single resistance variant	Mycobacterium tuberculosis	isoniazid	Card DatabaseResFinder DatabaseReslit	Confirmed
inhA Enoyl-(acyl-carrier-protein) reductase	I95T	-	-	Mycobacterium tuberculosis	isoniazid	ResFinder DatabaseReslit	Confirmed