Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
inhA enoyl-(acyl-carrier-protein) reductase | S531L | - | - | Mycobacterium tuberculosis | isoniazid | Reslit | Candidate |
inhA enoyl-(acyl-carrier-protein) reductase | S94A | mutant (S94A) copy of the inhA gene, reduces the effectiveness of INH-NAD inhibition, single resistance variant | Mycobacterium smegmatis, Mycobacterium tuberculosis | isoniazidethionamideethambutol | Card DatabaseResFinder DatabaseReslit | Confirmed | |
| S94L | - | - | Mycobacterium tuberculosis | isoniazid | ResFinder Database | Established | |
inhA enoyl-ACP reductase | S94P | - | - | Mycobacterium tuberculosis | ethionamide | Reslit | Candidate |
| S94W | - | - | Mycobacterium tuberculosis | isoniazid | ResFinder Database | Established | |
inhA InhA protein | T15A | - | - | - | isoniazid | Reslit | Candidate |
| T162S | - | single resistance variant | Mycobacterium tuberculosis | isoniazid | Card Database | Established | |
inhA enoyl-(acyl-carrier-protein) reductase | T8A | - | - | Mycobacterium tuberculosis | isoniazid | Reslit | Supported |
inhA enoyl-(acyl-carrier-protein) reductase | T8C | - | - | Mycobacterium tuberculosis | isoniazid | Reslit | Supported |
inhA enoyl-(acyl-carrier-protein) reductase | V136A | - | Mycobacterium tuberculosis | isoniazid | Reslit | Candidate |
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