Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
katG catalase-peroxidase | M255I | - | single resistance variant | Mycobacterium tuberculosis | isoniazid | Card DatabaseReslit | Confirmed |
katG catalase-peroxidase | M255Y | - | single resistance variant | Mycobacterium tuberculosis | isoniazid | Card DatabaseReslit | Confirmed |
katG catalase-peroxidase | M257I | - | - | Mycobacterium tuberculosis | isoniazid | Reslit | Candidate |
katG KatG enzyme, a catalase-peroxidase involved in the activation of isoniazid (INH) | M257V | - | single resistance variant | Mycobacterium tuberculosis | isoniazid | Card DatabaseReslit | Confirmed |
| M420T | - | single resistance variant | Mycobacterium tuberculosis | isoniazid | Card Database | Established | |
| M624V | - | single resistance variant | Mycobacterium tuberculosis | isoniazid | Card Database | Established | |
| N133T | - | single resistance variant | Mycobacterium tuberculosis | isoniazid | Card Database | Established | |
katG catalase-peroxidase | N138D | - | single resistance variant | Mycobacterium tuberculosis | isoniazid | Card DatabaseReslit | Confirmed |
katG ketoacyl-ACP synthase III | N138H | - | - | Mycobacterium tuberculosis | isoniazid | Reslit | Supported |
katG catalase-peroxidase | N138S | - | single resistance variant | Mycobacterium tuberculosis | isoniazid | Card DatabaseReslit | Confirmed |
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