Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
penA β-lactamase	A172V	-	-	Burkholderia thailandensis	ceftazidime	Reslit	Candidate
penA penicillin-binding protein 2	A311V	-	confers high-level resistance to expanded-spectrum cephalosporins, penicillin-binding protein PBP2 PenA	Neisseria gonorrhoeae	ceftizoximeceftriaxonecefixime+4 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
penA Penicillin-binding protein 2	A318V	-	-	Neisseria gonorrhoeae	cefixime	Reslit	Candidate
penA penicillin-binding protein 2	A328P	-	-	Neisseria gonorrhoeae	ceftriaxone	Reslit	Candidate
penA penicillin-binding protein 2 (PBP-2)	A376P	-	-	Neisseria gonorrhoeae	cephalosporins	Reslit	Candidate
penA Penicillin-binding protein 2	A488V	-	-	Neisseria gonorrhoeae	cefixime	Reslit	Candidate
penA	A501AA	-	penicillin-binding protein PBP2 PenA	Neisseria gonorrhoeae	cephalosporins	Reference Gene Catalog	Established
penA Penicillin-Binding Protein 2	A501P	-	reduced reactivity for β-lactams, penicillin-binding protein PBP2 PenA	Neisseria gonorrhoeae, Neisseria meningitidis	ceftriaxonecefiximeceftazidime+1 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
penA penicillin-binding protein 2	A501R	-	-	Neisseria gonorrhoeae	cefiximeceftriaxone	Reslit	Candidate
penA penicillin-binding protein 2	A501S	-	-	Neisseria gonorrhoeae	cefiximeceftriaxone	Reslit	Candidate