Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
penA β-lactamase	N170G	-	-	Burkholderia thailandensis	ceftazidime	Reslit	Candidate
penA β-lactamase	N170H	-	-	Burkholderia thailandensis	ceftazidime	Reslit	Candidate
penA β-lactamase	N170K	-	-	Burkholderia thailandensis	ceftazidime	Reslit	Candidate
penA Penicillin-binding protein 2	N506H	-	-	Neisseria gonorrhoeae	cefixime	Reslit	Candidate
penA penicillin-binding protein 2	N512Y	-	decreased susceptibility, reduced reactivity for β-lactams, decreased susceptibility to cefixime and ceftriaxone, penicillin-binding protein PBP2 PenA	Neisseria gonorrhoeae, Neisseria meningitidis	ceftriaxonecefiximeceftazidime+1 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
penA penicillin-binding protein 2	N513Y	-	-	Neisseria gonorrhoeae	ceftriaxonecefixime	Reslit	Candidate
penA β-lactamase	P167S	-	increased resistance	Burkholderia pseudomallei	ceftazidime	Reslit	Supported
penA penicillin-binding protein 2	P551L	-	penicillin-binding protein PBP2 PenA	Neisseria gonorrhoeae	cefiximepenicillincephalosporins+3 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
penA Penicillin-Binding Protein 2	P551S	-	reduced reactivity for β-lactams, penicillin-binding protein PBP2 PenA	Neisseria gonorrhoeae, Neisseria meningitidis	ceftriaxonecefiximecephalosporins+3 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
penA penicillin-binding protein 2	P552V	-	-	Neisseria gonorrhoeae	cefiximeceftriaxone	Reslit	Candidate