Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
penA penicillin-binding protein 2 | Q291R | - | - | Neisseria gonorrhoeae | ceftriaxone | Reslit | Candidate |
penA β-lactamase | R164H | - | - | Burkholderia thailandensis | ceftazidime | Reslit | Candidate |
penA β-lactamase | R164S | - | - | Burkholderia thailandensis | ceftazidime | Reslit | Candidate |
penA Penicillin-binding protein 2 | R356H | - | - | Neisseria gonorrhoeae | cefixime | Reslit | Candidate |
penA β-lactamase | R7K | - | no effect on PenA activity | Burkholderia pseudomallei | ceftazidimeamoxicillin clavulanic acid | Reslit | Candidate |
penA penicillin-binding protein 2 | S341P | - | - | Neisseria gonorrhoeae | ceftriaxone | Reslit | Candidate |
penA penicillin-binding protein 2 | S363C | - | had only a minor effect on acylation (1.5-fold decrease) | Neisseria gonorrhoeae | penicillin | Reslit | Candidate |
penA penicillin-binding protein 2 | S363D | - | lowered the acylation rate of penicillin G by 7-fold | Neisseria gonorrhoeae | penicillin | Reslit | Candidate |
penA β-lactamase | S72F | - | increased resistance | Burkholderia pseudomallei | amoxicillinclavulanic acidamoxicillin clavulanic acid | Reslit | Candidate |
penA class A beta-lactamase | T147A | - | - | Burkholderia pseudomallei | ceftazidime | Reslit | Candidate |
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