Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| K66R | - | single resistance variant, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA | Staphylococcus aureus | daptomycin | Card DatabaseReference Gene Catalog | Confirmed | |
pgsA phosphatidylglycerophosphate synthase | R579L | - | - | Staphylococcus aureus | daptomycin | Reslit | Candidate |
pgsA CDP-diacylglycerol–glycerol-3-phosphate 3-phosphatidyltransferase | S177F | - | single resistance variant, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA | Staphylococcus aureus | daptomycin | Card DatabaseReference Gene CatalogReslit | Confirmed |
pgsA CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase | T33N | - | - | Staphylococcus aureus | daptomycin | Reslit | Candidate |
pgsA phosphatidylglycerolphosphate synthase | T70P | - | decreased PgsA activity | Enterococcus faecium | daptomycin | Reslit | Candidate |
pgsA phosphatidylglycerolphosphate synthase | V44P | - | - | Escherichia coli | gentamicin | Reslit | Candidate |
pgsA CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase | V59N | - | single resistance variant, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA | Staphylococcus aureus | daptomycin | Card DatabaseReference Gene CatalogReslit | Confirmed |
| - | - | - | gentamicin | Reslit | Candidate | ||
pheS phenylalanyl-tRNA synthase | F254S | - | - | Staphylococcus aureus, Mammaliicoccus sciuri | oxacillin | Reslit | Candidate |
pheS phenylalanine--tRNA ligase | G94R | - | - | - | colistin | Reslit | Candidate |
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