Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pgi glucose-6-phosphate isomerase	G105E	-	-	Pseudomonas aeruginosa	aztreonam	Reslit	Candidate
pgm phosphoglucomutase	F266L	-	-	Escherichia coli	ceftriaxone	Reslit	Candidate
pgm phosphoglucomutase	P121L	-	-	Escherichia coli	ceftriaxone	Reslit	Candidate
pgsA CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase	A64V	-	single resistance variant, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA	Staphylococcus aureus	daptomycin	Card DatabaseReference Gene CatalogReslit	Confirmed
pgsA phosphatidylglycerolphosphate synthase	G122D	-	-	Staphylococcus capitis	daptomycin	Reslit	Candidate
pgsA phosphatidylglycerophosphate synthase	G147D	-	abolishing phosphatidylglycerophosphate synthase activity	Corynebacterium striatum	daptomycin	Reslit	Candidate
pgsA phosphatidylglycerophosphate synthase	G170D	-	-	Staphylococcus aureus	daptomycin	Reslit	Candidate
pgsA CDP-diacylglycerol-glycerol-3-phosphate-3-phosphatidyltransferase	G52S	-	-	Streptococcus mitis, S. oralis	daptomycin	Reslit	Candidate
pgsA CDP-diacylglycerol–glycerol-3-phosphate 3-phosphatidyltransferase	K135E	-	-	Staphylococcus aureus	daptomycin	Reslit	Candidate
pgsA CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase	K65R	-	-	Staphylococcus aureus	daptomycin	Reslit	Candidate