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In vitro selection of resistance to clinafloxacin, ciprofloxacin, and trovafloxacin in Streptococcus pneumoniae.

PMID: 109918542000

0gene entries

10mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
parC	S79Y	-	-	Streptococcus pneumoniae	Clinafloxacin\|Ciprofloxacin\|Trovafloxacin	Reslit	-
parE	P454S	-	-	Streptococcus pneumoniae	Clinafloxacin\|Ciprofloxacin\|Trovafloxacin	Reslit	-
gyrA	S81Y	-	-	Streptococcus pneumoniae	Clinafloxacin\|Ciprofloxacin\|Trovafloxacin	Reslit	-
parE	P454A	-	-	Streptococcus pneumoniae	Clinafloxacin\|Ciprofloxacin\|Trovafloxacin	Reslit	-
gyrA	S81F	-	-	Streptococcus pneumoniae	Clinafloxacin\|Ciprofloxacin\|Trovafloxacin	Reslit	-
parE	P454H	-	-	Streptococcus pneumoniae	Clinafloxacin\|Ciprofloxacin\|Trovafloxacin	Reslit	-
gyrA	S81L	-	-	Streptococcus pneumoniae	Clinafloxacin\|Ciprofloxacin\|Trovafloxacin	Reslit	-
gyrB	R445S	-	-	Streptococcus pneumoniae	Clinafloxacin\|Ciprofloxacin\|Trovafloxacin	Reslit	-
gyrB	G406S	-	-	Streptococcus pneumoniae	Clinafloxacin\|Ciprofloxacin\|Trovafloxacin	Reslit	-