Genetic Heterogeneity in pbp Genes among Clinically Isolated Group B Streptococci with Reduced Penicillin Susceptibility.

PMID: 188099362008

Key Findings

Mutations in pbp2x are associated with reduced penicillin susceptibility

0gene entries

6mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp2x	F395L	-	reduced penicillin susceptibility	Streptococcus agalactiae, Group B	penicillin	Reslit	-
pbp2b	T567I	-	-	Group B	penicillin	Reslit	-
pbp1a	G648A	-	-	Streptococcus agalactiae	penicillin	Reslit	-
pbp2a	E63K	-	reduced penicillin susceptibility	Streptococcus agalactiae	penicillin	Reslit	-
pbp1b	L41S	-	-	Group B	penicillin	Reslit	-