Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.
PMID: 207136792010
Key Findings
Previously reported
0gene entries
17mutation entries
AMR Mutations
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| gyrA | D94N | - | - | Mycobacterium tuberculosis | fluoroquinolones | Reslit | - |
| gyrA | R128S | - | - | Mycobacterium tuberculosis | fluoroquinolones | Reslit | - |
| rpoB | H526Y | - | - | Mycobacterium tuberculosis | rifampin | Reslit | - |
| gyrA | Y129C | - | - | Mycobacterium tuberculosis | fluoroquinolones | Reslit | - |
| katG | E217G | - | - | Mycobacterium tuberculosis | isoniazid | Reslit | - |
| rpoB | Q510P | - | - | Mycobacterium tuberculosis | rifampin | Reslit | - |
| rpoB | D516V | - | - | Mycobacterium tuberculosis | rifampin | Reslit | - |
| katG | S315T | - | - | Mycobacterium tuberculosis | isoniazid | Reslit | - |
| katG | R463L | - | - | Mycobacterium tuberculosis | isoniazid | Reslit | - |
| katG | D329A | - | - | Mycobacterium tuberculosis | isoniazid | Reslit | - |
| rpoB | S531L | - | - | Mycobacterium tuberculosis | rifampin | Reslit | - |
| gyrA | D94G | - | - | Mycobacterium tuberculosis | fluoroquinolones | Reslit | - |
| rpoB | L511V | - | - | Mycobacterium tuberculosis | rifampin | Reslit | - |
| gyrA | A90V | - | - | Mycobacterium tuberculosis | fluoroquinolones | Reslit | - |
| gyrA | S95T | - | - | Mycobacterium tuberculosis | fluoroquinolones | Reslit | - |
| rrs | - | - | Mycobacterium tuberculosis | amikacin|kanamycin|capreomycin | Reslit | - | |
| rrs | - | - | Mycobacterium tuberculosis | amikacin|kanamycin|capreomycin | Reslit | - |