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Key Findings
The study identifies three new resistance genes, erm(42), msr(E), and mph(E), responsible for macrolide, triamilide, and lincosamide resistance in Pasteurella multocida. These genes were experimentally validated through cloning and antimicrobial susceptibility testing.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| erm(42) | 1 | rRNA methylase | MacrolideLincosamideQUINUPRISTINPRISTINAMYCIN IACLINDAMYCINLINCOMYCINERYTHROMYCINVIRGINIAMYCIN S |
| Card DatabaseReference Gene CatalogResFinder DatabaseReslit | - |
| mph(E) | 1 |
| macrolide phosphotransferase |
Macrolide |
|
Reslit |
| - |
| msr(E) | 1 | - | QUINUPRISTINPRISTINAMYCIN IAAZITHROMYCINERYTHROMYCINVIRGINIAMYCIN S |
| ResFinder Database | - |
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