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Real-time PCR and high-resolution melt analysis for rapid detection of Mycobacterium leprae drug resistance mutations and strain types.

PMID: 221709232012

Key Findings

Detected in clinical strains

0gene entries

5mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB	H451Y	CAC->TAC	-	Mycobacterium leprae	Rifampin	Reslit	-
folP1	P55L	CCC->CTC	-	Mycobacterium leprae	Dapsone	Reslit	-
rpoB	D441Y	GAT->TAT	-	Mycobacterium leprae	Rifampin	Reslit	-
gyrA	A91V	GCA->GTA	-	Mycobacterium leprae	Fluoroquinolones	Reslit	-
rpoB	S456L	TCG->TTG	-	Mycobacterium leprae	Rifampin	Reslit	-