Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure.

PMID: 274113852016Europe

Key Findings

The study identifies multiple genetic mutations in Salmonella enterica Typhimurium that contribute to biocide and antibiotic resistance, including changes in genes such as fabI, ftsK, yeaN, mipA, asnA, aarF, tolA, motB, tdcA, garA, and bigA.

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8gene entries

15mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
aarF	1	Ubiquinone biosynthesis protein	TriclosanBenzalkonium chlorideChlorhexidine	Salmonella enterica serovar Typhimurium	Reslit	-
asnA	1	Asparagine synthetase A	TriclosanBenzalkonium chlorideChlorhexidine	Salmonella enterica serovar Typhimurium	Reslit	-
bigA

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
asnA	-	A74T	-	Salmonella enterica	Triclosan\|Benzalkonium chloride\|Chlorhexidine	Reslit	-
ftsK	-	A780T	-	Salmonella enterica	Triclosan\|Benzalkonium chloride\|ChlorhexidineTriclosan	Reslit	-
ftsK	-	A793T	-	Salmonella enterica

Browse Papers

Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure.

AMR Genes

AMR Mutations