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Key Findings
Among the five isolates that were resistant to RMP various mutations of the rpoB gene were detected. The types of mutations were similar to those found in a previous study from Greek patients affecting most commonly codons 531 and 526.
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| H526D | - | - | Mycobacterium tuberculosis | Rifampicin | Reslit | - | |
| H526Y | - | - | Mycobacterium tuberculosis | Rifampicin | Reslit | - | |
| S531L | - | - | Mycobacterium tuberculosis | Rifampicin | Reslit | - | |
| - | - | Mycobacterium tuberculosis | Isoniazid | Reslit | - | ||
| - | - | Mycobacterium tuberculosis | Isoniazid | Reslit | - |
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