Key Findings

The study identified various beta-lactamase genes including bla CTX-M-27, bla CTX-M-15, bla CTX-M-14, and bla CMY-2 in ESBL/AmpC-producing E. coli isolates from companion dogs in Japan. Additionally, fluoroquinolone resistance was linked to mutations in gyrA, parC, and parE genes, while polymyxin resistance was associated with a mutation in pmrB.