Rapid and Ultrasensitive Detection of Mutations and Genes Relevant to Antimicrobial Resistance in Bacteria.

PMID: 335525532021

Key Findings

The study presents a nanosensor-based assay for detecting antimicrobial resistance mutations and genes, including ampR D135G and G154R mutations and vanA, vanB, and vanD genes in Pseudomonas aeruginosa and Enterococcus faecium.

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4gene entries

2mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
ampR	1	transcriptional regulator	Beta-lactams	Pseudomonas aeruginosa	Reslit	-
vanA	1	vancomycin resistance gene	Vancomycin	Enterococcus faecium	Reslit	-
vanB	1	vancomycin resistance gene	Vancomycin	Enterococcus faecium

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ampR	D135G	-	-	Pseudomonas aeruginosa, Enterococcus faecium	Beta-lactam	Reslit	-

Browse Papers

Rapid and Ultrasensitive Detection of Mutations and Genes Relevant to Antimicrobial Resistance in Bacteria.

AMR Genes

AMR Mutations