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Identification of Multiple Low-Level Resistance Determinants and Coselection of Motility Impairment upon Sub-MIC Ceftriaxone Exposure in Escherichia coli.

PMID: 347874462021

Key Findings

mutations in envZ contribute to low-level ceftriaxone resistance

0gene entries

8mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
envZ	E212V	-	-	Escherichia coli	Ceftriaxone	Reslit	-
envZ	S242G	-	-	Escherichia coli	Ceftriaxone	Reslit	-
ompR	M197R	-	-	Escherichia coli	Ceftriaxone	Reslit	-
pgm	F266L	-	-	Escherichia coli	Ceftriaxone	Reslit	-
ompR	R150C	-	-	Escherichia coli	Ceftriaxone	Reslit	-
mgrB	C28F	-	-	Escherichia coli	Ceftriaxone	Reslit	-
pgm	P121L	-	-	Escherichia coli	Ceftriaxone	Reslit	-
marR	V66A	-	-	Escherichia coli	Ceftriaxone	Reslit	-