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Key Findings
The study identified a high prevalence of aminoglycoside and tetracycline resistance genes, including aph(3')-IIIa, ermB, mcr-1, qnrB19, and tetQ, in hospitalized patients from a high animal husbandry region. Unique resistance genes and mutations, such as dfrF and gyrB, were noted at discharge.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| aph(3')-IIIa | 1 | aminoglycoside phosphotransferase | Aminoglycoside |
| Reslit | - |
| erm(B) | 1 | methylase enzyme | MacrolideLincosamideStreptogramin b |
| Reslit | - |
| mcr-1 | 1 | polymyxin resistance protein |
Colistin |
|
Reslit |
| - |
| qnrB | 1 | quinolone resistance protein | Fluoroquinolone |
| Reslit | - |
| tet(Q) | 1 | ribosomal protection protein | Tetracycline |
| Reslit | - |
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