Analysis of antimicrobial resistance patterns and genetic mutations in Helicobacter pylori from West Bengal, India depicting escalating clarithromycin and high levofloxacin resistance.

PMID: 409994742025West Bengal, India

Key Findings

The study identifies the A2143G mutation in the 23SrRNA gene as the primary cause of clarithromycin resistance in H. pylori isolates from West Bengal, India. It also reports multiple mutations in the gyrA gene associated with levofloxacin resistance and specific amino acid changes in pbp1A linked to amoxicillin resistance.

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1gene entry

26mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
pbp1a	1	penicillin-binding protein 1A	Amoxicillin	Helicobacter pylori	Reslit	-

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp1a	S543H	-	-	-	Amoxicillin	Reslit	-
pbp1a	E406A	-	-	-	Amoxicillin	Reslit	-
gyrA	N87Y	-	-	-	Levofloxacin	Reslit	-

Browse Papers

Analysis of antimicrobial resistance patterns and genetic mutations in Helicobacter pylori from West Bengal, India depicting escalating clarithromycin and high levofloxacin resistance.

AMR Genes

AMR Mutations