Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
blaPenA β-lactamase | P167S | - | - | - | carbapenems | Reslit | Candidate |
blaPenI β-lactamase | C69Y | - | - | Escherichia coli, Burkholderia pseudomallei | ceftazidime | Reslit | Candidate |
blaPenI β-lactamase | P167S | - | - | Escherichia coli, Burkholderia pseudomallei | ceftazidime | Reslit | Candidate |
blaPER-4 beta-lactamase | - | reduced avibactam affinity and high-level CZA resistance | Pseudomonas aeruginosa | ceftazidimeceftazidime avibactam | Reslit | Candidate | |
blaPER Extended-spectrum beta-lactamase | S164F | - | - | - | cephalosporins | Reslit | Candidate |
blaROB-1 β-lactamase | A237T | - | increased resistance to extended-spectrum cephalosporins and β-lactam-β-lactamase inhibitor combinations | Escherichia coli | cefotaximeamoxicillin clavulanic acid | Reslit | Candidate |
blaROB-1 β-lactamase | L169S | - | increased resistance to extended-spectrum cephalosporins | Escherichia coli | cefotaxime | Reslit | Candidate |
blaROB-1 β-lactamase | R164W | - | increased resistance to extended-spectrum cephalosporins and β-lactam-β-lactamase inhibitor combinations | Escherichia coli | cefotaximeamoxicillin clavulanic acid | Reslit | Candidate |
blaSHV-1 beta-lactamase | - | - | Klebsiella pneumoniae | ceftazidimepiperacillin tazobactam | Reslit | Candidate | |
blaSHV-1 beta-lactamase | D104K | - | - | Escherichia coli | cefotaximeceftazidime | Reslit | Candidate |
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