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Explore scientific publications on antimicrobial resistance
Explore scientific publications on antimicrobial resistance
Key Findings
The study characterizes the vanD gene cluster and a novel insertion element, IS_Efm1, in a vancomycin-resistant Enterococcus faecium strain isolated in Canada. The vanD operon is constitutively expressed, and IS_Efm1 interrupts the ddl gene, affecting d-Ala-d-Ala ligase activity.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| vanD | 1 | d-alanine-d-alanine ligase | VancomycinVANCOMYCIN |
| Reference Gene CatalogReslit | - |
| vanH-D | 1 | D-lactate dehydrogenase VanH-D | VANCOMYCIN |
| Reference Gene Catalog | - |
| vanR-D |
| vancomycin resistance response regulator transcription factor VanR-D |
VANCOMYCIN |
|
Reference Gene Catalog |
| - |
| vanX-D | 1 | D-Ala-D-Ala dipeptidase VanX-D | VANCOMYCIN |
| Reference Gene Catalog | - |
| vanY-D | 1 | transpeptidase-like D-Ala-D-Ala carboxypeptidase VanY-D | VANCOMYCIN |
| Reference Gene Catalog | - |
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