Key Findings

The study characterizes the vanC-2 gene cluster in Enterococcus casseliflavus ATCC 25788, identifying genes involved in vancomycin resistance, including vanC-2, vanXY C-2, vanT C-2, vanR C-2, and vanS C-2. These genes contribute to the production of cell wall precursors that replace d-alanine with d-serine, reducing vancomycin binding.