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Key Findings
The study identifies and characterizes the Vga proteins, including vga(A), vga(A)v, vga(B), and Lmo0919, as conferring resistance to streptogramin A (SGA) and lincosamides in staphylococci. It also shows that vga(B) increases resistance to pristinamycin, a combination of SGA and SGB.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| lmo0919 | 1 | ATP-binding cassette (ABC) transporter | streptogramin a (sga)lincosamides |
| Reslit | - |
| vga(A) | 1 | ATP-binding cassette (ABC) transporter | streptogramin a (sga)lincosamides |
| Reslit | - |
| vga(a)v | 1 |
| ATP-binding cassette (ABC) transporter |
streptogramin a (sga)lincosamides |
|
Reslit |
| - |
| vga(B) | 1 | ATP-binding cassette (ABC) transporter | streptogramin a (sga)streptogramin b (sgb)pristinamycin (pt) |
| Reslit | - |
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