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Key Findings
The study characterizes the vanC cluster in Enterococcus gallinarum strains with constitutive and inducible vancomycin resistance, identifying key genes and mutations involved in glycopeptide resistance mechanisms.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| vanC1 | 1 | protein involved in the synthesis of d-Ser and its incorporation into the growing peptidoglycan chain | vancomycin |
| Reslit | - |
| vanR-C | 1 | protein exhibiting structural homology with members of two component regulatory systems | vancomycin |
| Reslit | - |
| vanS-C | 1 | sensor kinase protein | vancomycin |
Reslit |
| - |
| vanTc | 1 | protein involved in the synthesis of d-Ser and its incorporation into the growing peptidoglycan chain | vancomycin |
| Reslit | - |
| vanXY-C | 1 | proteins involved in the hydrolysis of d-Ala-ending precursors | vancomycin |
| Reslit | - |
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