Simultaneous detection of nine antibiotic resistance-related genes in Streptococcus agalactiae using multiplex PCR and reverse line blot hybridization assay.

PMID: 163776872006Asia|Australasia

Key Findings

The study developed a multiplex PCR and reverse line blot hybridization assay to detect nine antibiotic resistance-related genes in Streptococcus agalactiae, including erm(B), erm(A/TR), mef(A/E), tet(M), tet(O), aphA-3, aad-6, int-Tn, and mreA. These genes were found to be associated with resistance to macrolides, lincosamides, streptogramin B, tetracyclines, and aminoglycosides.

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5gene entries
0mutation entries

AMR Genes

Gene NameEncodesConfers Resistance ToOrganismsDatabaseStatus
apha-3Family: apha
kanamycin phosphotransferase
aminoglycosides
  • Streptococcus agalactiae
ReslitNot Validated
erm(B)ribosomal methylase
macrolideslincosamidesstreptogramin b
  • Streptococcus agalactiae
ReslitNot Validated
mef(a/e)efflux pump
macrolides
  • Streptococcus agalactiae
ReslitNot Validated
tet(M)ribosomal protection protein
tetracyclines
  • Streptococcus agalactiae
ReslitNot Validated
tet(O)efflux pump
tetracyclines
  • Streptococcus agalactiae
ReslitNot Validated