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Fluoroquinolone resistance in Clostridium difficile isolates from a prospective study of C. difficile infections in Europe.

PMID: 184803382008

Key Findings

Thr82Ile was the most frequent amino acid change identified

0gene entries

5mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	T82I	-	-	Clostridium difficile	moxifloxacin\|ciprofloxacin\|gatifloxacin\|levofloxacin	Reslit	-
gyrB	S416A	-	-	Clostridium difficile	moxifloxacin\|ciprofloxacin\|gatifloxacin\|levofloxacin	Reslit	-
gyrB	D426N	-	-	Clostridium difficile	moxifloxacin\|ciprofloxacin\|gatifloxacin\|levofloxacin	Reslit	-
gyrB	D426V	-	-	Clostridium difficile	moxifloxacin\|ciprofloxacin\|gatifloxacin\|levofloxacin	Reslit	-
gyrB	R447K	-	-	Clostridium difficile	moxifloxacin\|ciprofloxacin\|levofloxacin	Reslit	-