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Key Findings
The study identifies blaOXA-51-like, blaOXA-58-like, blaDIM-1, and blaVIM carbapenemase genes in hospital Enterobacteriaceae isolates from Sierra Leone, highlighting the presence of these resistance genes in non-Acinetobacter species and emphasizing the need for molecular surveillance of carbapenemase gene circulation.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| blaDIM | 1 | metallo-beta-lactamase | Carbapenem |
| Reslit | - |
| blaOXA | 1 | carbapenemase | Carbapenem |
| Reslit | - |
| blaoxa-58-like | 1 | carbapenemase |
Carbapenem |
|
Reslit |
| - |
| blaVIM | 2 | subclass B1 metallo-beta-lactamase VIM-30, VIM beta-lactamase | MEROPENEMERTAPENEMAMOXICILLINCEFOXITINIMIPENEMCEFIXIMECEFEPIMEAMPICILLIN+CLAVULANIC ACIDAMPICILLIN+7 more |
| Card DatabaseReference Gene CatalogResFinder DatabaseReslit | - |
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