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Key Findings
The study identifies mutations in gyrA and parC genes contributing to fluoroquinolone resistance in Group B Streptococcus (GBS) isolates, along with the presence of resistance genes tetM, ermB, and lnuB. A new integrative and conjugative element (ICE) carrying tetM and gyrA was also identified.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| erm(B) | 1 | erythromycin ribosome methyltransferase | Erythromycin |
| Reslit | - |
| lnu(B) | 1 | lincomycin nucleotidyltransferase | Clindamycin |
| Reslit | - |
| tet(M) | 1 | tetracycline resistance protein | Tetracycline |
|
Reslit |
| - |
| S79Y |
| - |
| - |
| - |
Fluoroquinolones |
Reslit |
| - |
| I219F | - | - | - | Fluoroquinolones | Reslit | - |
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