Evolution and emergence of multidrug-resistant Mycobacterium tuberculosis in Chisinau, Moldova.

PMID: 344317622021

Key Findings

Multiple gyrA mutations (D94G, D94A, A90V) confer resistance to fluoroquinolones.

0gene entries

6mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	D94G	-	-	-	Fluoroquinolones	Reslit	-
katG	S315T	-	-	-	Isoniazid	Reslit	-
rpsL	K88R	-	-	-	Streptomycin	Reslit	-
gyrA	D94A	-	-	-	Fluoroquinolones	Reslit	-
rpoB	S450L	-	-	Mycobacterium tuberculosis	Rifampin	Reslit	-
gyrA	A90V	-	-	-	Fluoroquinolones	Reslit	-