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Genetic and in-silico approaches for investigating the mechanisms of ciprofloxacin resistance in Salmonella typhi: Mutations, extrusion, and antimicrobial resistance.

PMID: 393979802024

0gene entries

10mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	D87G	-	reduced ciprofloxacin binding affinity	Salmonella typhi	Ciprofloxacin	Reslit	-
parE	L416F	-	-	Salmonella enterica	Ciprofloxacin	Reslit	-
gyrA	S83Y	-	reduced ciprofloxacin binding affinity	Salmonella typhi	Ciprofloxacin	Reslit	-
parC	E84G	-	-	Salmonella typhi	Ciprofloxacin	Reslit	-
gyrA	D87N	-	reduced ciprofloxacin binding affinity	Salmonella typhi	Ciprofloxacin	Reslit	-
gyrB	S464F	-	-	Salmonella enterica	Ciprofloxacin	Reslit	-
parC	S80I	-	-	Salmonella typhi	Ciprofloxacin	Reslit	-
gyrA	S83F	-	reduced ciprofloxacin binding affinity	Salmonella typhi	Ciprofloxacin	Reslit	-
parC	E84K	-	-	Salmonella typhi	Ciprofloxacin	Reslit	-
parC	S80R	-	-	Salmonella typhi	Ciprofloxacin	Reslit	-