Tracing the evolutionary trajectory of the IncP-2 plasmid co-harboring bla (IMP-45) and bla (VIM-1): an outbreak of Pseudomonas aeruginosa co-producing IMP-45 and VIM-1 carbapenemases in China.

PMID: 406123922025China

Key Findings

The study documents an outbreak of P. aeruginosa co-producing VIM-1 and IMP-45 carbapenemases in a tertiary hospital in China, highlighting the emergence of highly resistant strains among transplant patients.

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2gene entries

1mutation entry

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaIMP	1	metallobeta-lactamase	Carbapenem	Pseudomonas aeruginosa	Reslit	-
blaVIM	1	metallobeta-lactamase	Carbapenem	Pseudomonas aeruginosa	Reslit	-

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp3	P527S	-	reduced aztreonam binding	Pseudomonas aeruginosa	Aztreonam	Reslit	-

Browse Papers

Tracing the evolutionary trajectory of the IncP-2 plasmid co-harboring bla (IMP-45) and bla (VIM-1): an outbreak of Pseudomonas aeruginosa co-producing IMP-45 and VIM-1 carbapenemases in China.

AMR Genes

AMR Mutations