Diagnostic performance of the Sanity 2.0 assay to detect resistance to rifampicin, isoniazid, and fluoroquinolones in tuberculosis.

PMID: 413692502026

Key Findings

Detected in discrepant cases where the assay identified resistance but WGS interpreted as susceptible.

0gene entries

5mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	D94V	A281T	-	-	Fluoroquinolones	Reslit	-
gyrB	D461N	G1381A	-	-	Fluoroquinolones	Reslit	-
gyrA	D89N	G266A	-	-	Fluoroquinolones	Reslit	-
rpoB	V170F	G508T	-	Mycobacterium tuberculosis	Rifampicin	Reslit	-
katG	-	G595A	-	-	Isoniazid	Reslit	-