Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
cfr methyltransferase | S39G | - | - | E. coli | hygromycintiamulin | Reslit | Candidate |
cfxA class 2e beta-lactamase | Y239D | - | associated with ceftazidime resistance | Prevotella | ceftazidime | Reslit | Candidate |
chiZ Cell division protein ChiZ | Y124H | - | - | Mycobacterium tuberculosis | amoxicillinmeropenem | Reslit | Candidate |
ciaH histidine protein kinase | T230P | - | activates the CiaRH system | Streptococcus pneumoniae | cefotaxime | Reslit | Candidate |
cirA catecholate siderophore receptor | - | - | Klebsiella pneumoniae | cefiderocol | Reslit | Candidate | |
| E133* | - | catecholate siderophore receptor CirA | Klebsiella pneumoniae | cefiderocol | Reference Gene Catalog | Established | |
| E388* | - | catecholate siderophore receptor CirA | Escherichia coli | cefiderocol | Reference Gene Catalog | Established | |
cirA Iron-catecholate outer membrane transporter | E465D | - | - | Escherichia coli | cefiderocol | Reslit | Candidate |
cirA siderophore receptor | G465D | - | - | Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae | cefiderocol | Reslit | Candidate |
| G75W | - | catecholate siderophore receptor CirA | Klebsiella pneumoniae | cefiderocol | Reference Gene Catalog | Established |
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