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Explore scientific publications on antimicrobial resistance
Explore scientific publications on antimicrobial resistance
Key Findings
The study identifies the spread of Escherichia coli strains with high-level resistance to cefotaxime and ceftazidime, primarily due to the presence of extended-spectrum beta-lactamases (ESBLs) such as CTX-M-15, CTX-M-14, and CTX-M-32. Additionally, other resistance genes like tetA, dfrA14, dfrA17, sul1, sul2, aac(6')Ib, and aac(3)IIb were found to contribute to multidrug resistance.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| aac(3)-IIb | 1 | aminoglycoside acetyltransferase | GentamicinTobramycin |
| Reslit | - |
| aac(6')-Ib | 1 | aminoglycoside acetyltransferase | GentamicinTobramycin |
| Reslit | - |
| blaCTX-M | 3 | extended-spectrum beta-lactamase | CefotaximeCeftazidime |
| Reslit | - |
| dfrA14 | 1 | dihydrofolate reductase | Trimethoprim |
| Reslit | - |
| dfrA17 | 1 | dihydrofolate reductase | Trimethoprim |
| Reslit | - |
| sul1 | 1 | sulfonamide resistance protein | Sulfamethoxazole |
| Reslit | - |
| sul2 | 1 | sulfonamide resistance protein | Sulfamethoxazole |
| Reslit | - |
| tetA | 1 | tetracycline resistance protein | Tetracycline |
| Reslit | - |
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