Key Findings

The study introduces a modified carbapenem inactivation method, CIMTris, which shows higher sensitivity than the mCIM for detecting carbapenemase production in Acinetobacter and Pseudomonas species. Several carbapenemase genes, including blaIMP-10, blaIMP-14, blaIMP-15, blaIMP-26, blaIMP-34, blaIMP-43, blaIMP-44, blaIMP-51, blaNDM-1, blaVIM-1, blaVIM-2, blaGES-5, blaGES-6, blaOXA-23, blaOXA-58, blaOXA-72, blaOXA-69, blaOXA-82, blaOXA-98, and blaOXA-51-like, were identified and validated in this study.