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Key Findings
Mutations in PhoP/PhoQ lead to constitutive activation of the arnBCADTEF operon and pmrC.
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| D191Y | - | - | - | Colistin | Reslit | - | |
| T157P | - | - | - | Colistin | Reslit | - | |
| G183V | - | - | - | Colistin | Reslit | - | |
| R16C | - | - | - | Colistin | Reslit | - | |
| R256G | - | - | - | Colistin | Reslit | - | |
| D150G | - | - | - | Colistin | Reslit | - | |
| Q10L | - | - | - | Colistin | Reslit | - | |
| C28Y | - | - | Klebsiella pneumoniae | Colistin | Reslit | - | |
| G53C | - | - | - | Colistin | Reslit | - | |
| N141Y | - | - | - | Colistin | Reslit | - | |
| R114A | - | - | - | Colistin | Reslit | - | |
| G53S | - | - | - | Colistin | Reslit | - | |
| P151L | - | - | - | Colistin | Reslit | - |
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