Application of mNGS in the Etiological Analysis of Lower Respiratory Tract Infections and the Prediction of Drug Resistance.

PMID: 351710072022

Key Findings

The study identified several AMR genes using mNGS, including bla OXA-23, bla OXA-51, bla TEM, bla CTX-M, bla SHV, bla KPC, and mecA, which were associated with resistance to various antibiotics in different bacterial species.

View on PubMed

6gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaCTX-M	1	extended-spectrum beta-lactamase	PenicillinCephalosporinAztreonam	Escherichia coli Klebsiella pneumoniae Serratia marcescens	Reslit	-
blaKPC	1	carbapenemase	PenicillinCephalosporinAztreonamCarbapenem	Klebsiella pneumoniae	Reslit

Browse Papers

Application of mNGS in the Etiological Analysis of Lower Respiratory Tract Infections and the Prediction of Drug Resistance.

AMR Genes