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Key Findings
This study uses unsupervised machine learning to identify patterns in AMR genes, linking gene length and resistance class to resistance mechanisms. Key AMR genes identified include sul1, sul2, cat, blaTEM, vanA, aac(6')-Ib, aph(3')-IIIa, tet(M), and tet(O).
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| aac(6')-Ib | 1 | aminoglycoside N-acetyltransferase | GentamicinTobramycin |
| Reslit | - |
| aph(3')-IIIa | 1 | adenine phosphotransferase | Kanamycin |
| Reslit | - |
| blaTEM | 1 | beta-lactamase | Penicillin |
|
Reslit |
| - |
| catA1 | 1 | chloramphenicol acetyltransferase | Chloramphenicol |
| Reslit | - |
| sul1 | 1 | dihydropteroate synthase variant | Sulfonamide |
| Reslit | - |
| sul2 | 1 | dihydropteroate synthase variant | Sulfonamide |
| Reslit | - |
| tet(M) | 1 | ribosomal protection protein | Tetracycline |
| Reslit | - |
| tet(O) | 1 | ribosomal protection protein | Tetracycline |
| Reslit | - |
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