Whole-genome sequencing reveals transmission pattern and drug resistance of Mycobacterium tuberculosis intra- or inter-hosts.

PMID: 399062172024

0gene entries

26mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
katG	S315T	A943T	-	Mycobacterium tuberculosis	INHIsoniazid	Reslit	-
rpsL	K43R	A127G	-	-	Streptomycin	Reslit	-
rrs	-	A1401G	-	-	Amikacin\|Kanamycin	Reslit	-
rpsL	K88R	A263G	-	-	Streptomycin	Reslit	-
rpoB	H445R	C1333A	-	Mycobacterium tuberculosis	Rifampicin\|Rifabutin	Reslit	-
rpoB	H445D	C1333G	-	Mycobacterium tuberculosis	Rifampicin\|Rifabutin	Reslit	-
rpoB	H445Y	C1333T	-	Mycobacterium tuberculosis	Rifampicin\|Rifabutin	Reslit	-
embB	Q497P	C1490T	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	H1002R	C3004G	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
thyA	R235P	C703T	-	Mycobacterium tuberculosis	Para-aminosalicylic acid	Reslit	-
embB	D354A	G1060A	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	G406D	G1216A	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
rpoB	D435G	G1303C	-	Mycobacterium tuberculosis	Rifampicin\|Rifabutin	Reslit	-
rpoB	D435V	G1303T	-	Mycobacterium tuberculosis	Rifampicin\|Rifabutin	Reslit	-
rpoB	D545E	G1633A	-	Mycobacterium tuberculosis	Rifampicin\|Rifabutin	Reslit	-
gyrA	A90V	G268T	-	-	Fluoroquinolones	Reslit	-
gyrA	D94N	G280A	-	-	Fluoroquinolones	Reslit	-
gyrA	D94A	G280A	-	-	Fluoroquinolones	Reslit	-
gyrA	D94G	G280C	-	-	Fluoroquinolones	Reslit	-
gidB	A134E	G400A	-	-	Streptomycin	Reslit	-
rpoB	S450L	T1348C	-	Mycobacterium tuberculosis	Rifampicin\|Rifabutin	Reslit	-
rpoB	L452P	T1354C	-	Mycobacterium tuberculosis	Rifampicin\|Rifabutin	Reslit	-
embB	M306I	T916A	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	M306L	T916C	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	M306V	T916G	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-